Searchable abstracts of presentations at key conferences in endocrinology

ea0031p365 | Thyroid | SFEBES2013

The challenge of managing refractory amiodarone-induced Graves' disease in resistance to thyroid hormone

Moran Carla , Chatterjee V K K , Page M D , Owen Penny

A 42-year-old man with resistance to thyroid hormone (RTH) and a recognised thyroid hormone receptorβ mutation (R383C) mutation, presented with atrial fibrillation (AF) which was resistant to DC cardioversion until initiation of amiodarone therapy.As expected in RTH, his baseline TFTs were abnormal (FT4 34.6 pmol/l, TSH 2.27 mU/l), but rose further (FT4 45 pmol/l, TSH 0.93 mU/l) following commencement of amiodarone. However, sh...